ASAP IV Oral Antibiotic Duration

ANZPID-ASAP Guidelines for Antibiotic Duration and IV-Oral Switch in Children

Antibiotic duration and timing of the switch from intravenous to oral route for bacterial infections in children: systematic review and guidelines

Authors: The ANZPID-ASAP Group

Publisher: The Lancet Infectious Diseases

In the context of a global antibiotic resistance crisis, better evidence-based use of antibiotics has become imperative. This review and guideline provides practical and evidence-based advice on intravenous and oral duration of antibiotics for 36 paediatric infections. This document is the result of a large collaborative effort between the 22 contributing authors, the ANZPID-ASAP members who reviewed the review, and the journal editors who have brought this to publication.

The president of ASID Professor Cheryl Jones said, "These are a highly valuable series of evidence-based recommendations to guide when and how to step down from intravenous to oral antibiotics in childhood infections."

The impact of the review on patient management globally is also anticipated. "The opportunity to have these evidence-based recommendations in one location will be tremendously helpful," said Professor David W. Kimberlin, immediate past president of the Pediatric Infectious Diseases Society (PIDS), which is ASID’s North American counterpart, and guest speaker at this year's ASM. "They likely will lead to management changes well beyond Australia."

Access to the guideline

Systematic review: The Lancet Infectious Diseases has made the review free to access (link) and the guideline is in an edited table within the article.

Guideline: The guideline table is also available here in stand-alone format​, both in the full 4 page version (here), and in a modified 2 page version (here) for ease of use.

Lanyard card: ​We would like to know whether people would be interested in a lanyard version. We have created this for you to download and make your own if you are very enthusiastic (right click images - Lanyard front and Lanyard back).

Lanyard front Lanyard back

If you would be interested in us producing a lanyard card for you for the cost of production and postage only, please email ASID admin staff at admin@asid.net.au and leave your name and institution and how many you would potentially like (this doesn't commit you to anything). If there is enough interest we will produce one and let you know so you can order them.